|
Adaption of Behaviour by Pain and Sensory Processing| title | Adaption of Behaviour by Pain and Sensory Processing |
|---|
| start_date | 2024/04/22 |
|---|
| schedule | 15h15 |
|---|
| online | no |
|---|
| location_info | Room B10 |
|---|
| summary | Survival across animal species depends on the ability to generate appropriate responses to imminent threats, whether distant or at the body surface. The adaptive control of these responses becomes crucial following injury, signalled by the presence of pain. While hypersensitivity to pain acts as a protective mechanism for an injured site, reducing the risk of further damage, the broader impact of tonic pain on behavioural strategies is less clear. It is yet to be determined whether such pain influences a wider range of behavioural choices in response to environmental challenges. Here, we describe interactions between tonic pain, the pursuit of safety, and sensitivity to threats. We investigate the neural basis of these adaptive processes through precise chemogenetic and optogenetic manipulations in the mouse primary sensory cortex. Our findings suggest that primary sensory cortex plays key roles in linking pain and sensory processing with adaptive behaviours critical for survival. |
|---|
| responsibles | Allen |
|---|
Workflow history| from state (1) | to state | comment | date |
|---|
| submitted | published | | 2024/04/17 14:57 UTC |
| |
|