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Persistent activity in human frontal eye fields during the maintenance of spatial working memory, covert attention, and motor intention| old_uid | 210 |
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| title | Persistent activity in human frontal eye fields during the maintenance of spatial working memory, covert attention, and motor intention |
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| start_date | 2005/11/21 |
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| schedule | 11h-13h |
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| online | no |
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| details | Invité par Karine Doré-Mazars (équipe Exploration oculaire et perception) |
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| summary | Persistent activity during the delay period of a working memory task is compelling evidence that the activity reflects a memory representation. Frontal, parietal, and subcortical brain areas all show evidence of persistent activity during spatial working memory delays. My recent work, however, has focused not on which parts of the brain are active during working memory delays, but instead on what might persistent activity represent. In other words, what is being coded for by persistent activity? During a memory delay, one may need to keep active a past perceptual event, a retrospective sensory code, or a future action, a prospective motor code, in order to link events that are separated in time but are contingent upon one another. I will present data form a series of event-related fMRI studies that have focused on the role of human frontal eye fields (FEF) in spatial working memory, attention, and motor intention. These studies suggest that one mechanism by which the FEF supports spatial working memory is through the maintenance of saccadic intentions. However, other compelling data suggest that this is not the only mechanism used by the human FEF to support higher-level visuomotor cognition. |
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| responsibles | Cohen |
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