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Error-processing in patients with brain lesions : evidence from event-related potential studies| old_uid | 1747 |
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| title | Error-processing in patients with brain lesions : evidence from event-related potential studies |
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| start_date | 2006/11/13 |
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| schedule | 11h-12h30 |
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| online | no |
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| summary | When people make errors in choice-reaction-time tasks and we monitor the brain response with the event-related potential technique, a negative going deflection – the so-called error negativity – is consistently observed. Lesion studies with patients as well as localization studies with fMRI and EEG place the generator of the error negativity predominantly in the anterior cingulate region. A link between the generation of the error negativity and the activity of the mesencephalic dopamine system has been proposed. The model suggests that the error negativity is generated when a negative reinforcement learning signal is conveyed to the anterior cingulate via the mesencephalic dopamine system. Pathologies such as a cerebrovascular infarct or Parkinson’s disease that disrupt this pathway should thus modulate the error negativity. Behavioural and event-related potential data from these patients will be presented and discussed. |
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| responsibles | Cohen, Kergoat |
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