The rules of reconsolidation

old_uid3157
titleThe rules of reconsolidation
start_date2007/09/10
schedule10h
onlineno
detailsInvité par Sophie Tonel / CRI
summaryIt was thought that memories consolidate only once. Considerable evidence has now accumulated to demonstrate that when consolidated memories are remembered, they can undergo another consolidation-like process, called reconsolidation. Reconsolidation has now been found across paradigms and tasks suggesting that it is a fundamental process. The next questions that we need to address is how does a consolidated memory become un-consolidated” during reactivation. Furthermore, given that not all memories undergo reconsolidation what are the neurobiological mechanisms that determine when a memory will and will not undergo reconsolidation? We have identified some mechanisms in that must occur in order for fear memories to become “un-fixed” and begun to understand the principles of how behavioral conditions control whether a memory does or does not under go reconsolidation. Lastly, I will discuss the theoretical and historical issues surrounding interpretations of amnesia as being the absence of a memory vs the inability to retrieve the memory. I will discuss a new framework for testing this issue which has not been resolved
oncancelHoraire inhabituel
responsiblesDeris