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The influence of oscillations on models of the saccadic mechanism| old_uid | 4077 |
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| title | The influence of oscillations on models of the saccadic mechanism |
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| start_date | 2008/02/14 |
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| schedule | 11h |
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| online | no |
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| location_info | salle de réunion de l’U864 |
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| details | Journal Club de l’U864 |
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| summary | Saccadic oscillations are unwanted back-to-back saccades occurring one upon the other that produce a high-frequency oscillation of the eyes (usually 15-30 Hz). These may occur transiently in normal subjects, for example, around the orthogonal axis of a purely horizontal or vertical saccade, during combined saccade-vergence gaze shifts or during blinks. Some subjects may produce saccadic oscillations at will, usually with convergence. Pathological, involuntary saccadic oscillations such as flutter and opsoclonus are prominent in certain diseases. Three experimental findings on saccadic oscillations pushed forward the development of a new mathematical model of the saccadic system. Such new model of the premotor circuit for generating saccades includes brain stem burst neurons in the pontine paramedian reticular formation (PPRF), which show the physiological phenomenon of post-inhibitory rebound (PIR). This model makes saccadic oscillations because of the positive feedback among excitatory and inhibitory burst neurons. |
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| oncancel | changement de salle, horaire inhabituel |
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| responsibles | Farnè, Béranger, Soulier |
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