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Computational Biomechanical Studies of physiological flows| old_uid | 4548 |
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| title | Computational Biomechanical Studies of physiological flows |
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| start_date | 2008/04/07 |
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| schedule | 15h |
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| online | no |
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| location_info | salle 0D4 |
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| summary | Human cardiovascular system is always under the integrated nervous and
humoral control of the whole body, i.e., in homeostasis. Multiple feedback mechanisms with mutual interactions among systems, organs, and even tissues provide integrated control of the entire body. These control mechanisms have different spatial coverage, from the micro- to macroscale, and different time constants, from nanoseconds to decades. I think that these variations in scales should be taken into account in discussing phenomena in the cardiovascular system. In this background, we have been investigated the cardiovascular system
over micro to macro levels by using conjugated computational mechanics
analyzing fluid and solid interactions. In this study, I introduce our recent researches on the pulsatile blood flow from the heart, pulse wave propagation in large vessels, ATP transport in a cerebral artery with aneurysm, and the progress of cerebral aneurysm due to adaptation of arterial wall. I also introduce researches on the deformation of red blood cells in the flow field, blood flow considering more than 10 thousand of red blood cells' motion, and the effect of malaria on the
micro-circulation, and so on. I expect that biological phenomena, including disease processes, will be clarified in the future by integrating new understandings of macroscale and microscale hemodynamics, if we continue to be together with advances of related sciences and technologies. |
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| oncancel | Horaire inhabituel |
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| responsibles | Perthame |
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