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Brain plasticity and upper limb function after stroke:
some implications for rehabilitation| old_uid | 5190 |
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| title | Brain plasticity and upper limb function after stroke:
some implications for rehabilitation |
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| start_date | 2008/06/30 |
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| schedule | 16h15 |
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| online | no |
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| summary | Neuroimaging and neurophysiology techniques were used to study some aspects of cortical sensory and motor system reorganisation after stroke. Findings were related to clinical and behavioural measures of upper limb function in patients after stroke in the chronic phase. The diffusion tensor imaging (DTI) and the transcranial magnetis stimulation (TMS) findings suggest that structural and functional integrity of the CFT is essential to maintain function of the upper limb after stroke.
Using functional magnetic resonance imaging (fMRI) we found evidence for (i) cortical involvement in the hyperactive reflex response of flexor muscles upon passive stretch in stroke patients, (ii) reduced brain activity in sensorimotor circuits occuring with time post-stroke, and (iii) increased brain activity after intense training. The latter findings suggest a use-dependent modification of cortical activation patterns in the affected hand after stroke. |
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| responsibles | van Vreeswijk, Hansel |
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