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Synaptic specificity in the visual systemold_uid | 5475 |
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title | Synaptic specificity in the visual system |
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start_date | 2008/10/24 |
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schedule | 13h |
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online | no |
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location_info | Cruciform Building, Lecture Theatre 1 |
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summary | Josh Sanes has done pioneering work on the development and specificity of synaptic connections.Initially focusing on the neuromuscular junction, his group has moved towards examining synapses in the mammalian CNS, with an emphasis on retinal connectivity.A celebrated recent achievement by has been the creation of Brainbow mice (see picture below), which use combinatorial expression of fluorescent proteins to produce uniquely labelled neurons in a palette of colours. These mice should greatly facilitate the analysis and reconstruction of neural circuits. Sanes is the Director of the Harvard Center for Brain Science, the Editor-in-Chief of Neural Development, and is a member of the U.S. National Academy of Sciences. |
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responsibles | Lawrence |
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