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Molecular control of neocortical projection neuron identity and connectivity| old_uid | 7357 |
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| title | Molecular control of neocortical projection neuron identity and connectivity |
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| start_date | 2009/09/22 |
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| schedule | 11h |
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| online | no |
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| location_info | salle de conférence |
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| summary | Our laboratory investigates how neuronal identities and synaptic circuits form during development, and how these change during evolution of the mammalian brain. Our studies focus on the frontal lobe of the cerebral cortex due to its importance in higher cognitive functions and the remarkable complexity of its neuronal phenotypes, in particular the pyramidal (projection) neurons. Pyramidal neurons occupy a central position in all cortical circuits, constituting the sole output from and the largest input system to the cortex, as well as the major target of all inputs to the cortex. Our strategy is to identify mechanisms that are important for the specification, development, and evolutionary specializations of pyramidal neurons, and to investigate their roles using a variety of molecular and genetic approaches. |
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| responsibles | Vezoli |
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