| old_uid | 8227 |
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| title | Large-scale brain dynamics of visuomotor and oculomotor behavior: Insights from MEG and intracerebral EEG recordings |
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| start_date | 2010/02/22 |
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| schedule | 11h30 |
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| online | no |
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| details | invité par Suliann Ben Hamed, UMR5229 |
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| summary | Local and long-distance neural synchonization play a key role in mediating sensorimotor behavior. Although neuroimaging studies continue to play a fundamental role in the study of large-scale perceptuo-motor networks, the fine-scale temporal and oscillatory properties of such networks need to be investigated with high (millisecond) temporal resolution. I will present data using invasive and non-invasive electrophysiological techniques that investigate oculomotor behavior and visuomotor control. First, using Magnetoencephalography (MEG) we address the role of cerebral oscillations and long-range cortico-cortical coupling in mediating continuous visuomotor control. Beyond providing direct links between cortical activity and hand movement kinematics, our data reveal task-specific modulations of large-scale parieto-frontal activations across multiple frequency bands. In a separate study, we used stereotactic-EEG (SEEG) to record directly from various brain structures in implanted epilepsy patients while they performed a delayed saccade paradigm. The unique human intracranial findings we report suggest that high frequency activity in the gamma range (60-140 Hz) and long-range coupling (in alpha/beta range) might play a fundamental role in oculomotor planning as well as in a series of intricately related
neural processes such as visuomotor transformation and visuo-spatial attention. Finally, time permitting, I will present our real-time brain power visualization platforms: Brain TV and Brain Ball and discuss possible implications of our findings in the context of brain computer interfaces and neurofeedback applications.
Selected Refs:
Jerbi K, Ossandon T, Hamam CM, Senova S, Dalal S, Jung J,
Minotti L, Bertrand O, Berthoz AM, Kahane P and Lachaux J-P Task-Related
Gamma-Band Dynamics From an Intracerebral Perspective: Review and
Implications for Surface EEG and MEG Hum Brain Mapp., 2009 Jun;
30(6):1758-71.
Jerbi K, Lachaux J-P, N'Diaye K, Pantazis D, Leahy RM, Garnero L
and Baillet S, "Neural representation of hand speed in humans revealed
by MEG imaging" Proc. Nat. Acad. Sci. USA, 2007 May 1;104(18):7676-81.
Jerbi K, Freyermuth S, Dalal SS, Kahane P, Bertrand O, Berthoz
A, Lachaux J-P, Saccade Related Gamma-Band Activity in Intracerebral
EEG: Dissociating Neural from Ocular Muscle Activity. Brain Topogr. 2009
Jun; 22:18-23.
Jerbi K, Freyermuth S, Minotti L, Kahane P, Berthoz A and
Lachaux J-P, Watching Brain TV and Playing Brain Ball: Exploring novel
BCI strategies using real-time analysis of human intracranial data , Int
Rev Neurobiol. 2009;86:159-68.
Jerbi K and Bertrand O "Cross-frequency coupling in
parieto-frontal oscillatory networks during motor imagery revealed by
magnetoencephalography" in Front. Neurosci. 2009, 3, 1:3-4.
Jerbi K, Hamam CM, Ossandon T and Dalal SS Role of Posterior
Parietal Gamma Activity in Planning Prosccades and Antisccades J
Neurosci, 2008 Dec 17; 28(51):13713-5. |
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| responsibles | Béranger |
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