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Models of Antibiotic Resistance in Hospitals| old_uid | 8859 |
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| title | Models of Antibiotic Resistance in Hospitals |
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| start_date | 2010/06/08 |
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| schedule | 14h |
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| online | no |
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| location_info | salle 2E01 |
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| summary | Infections caused by antibiotic-resistant pathogens in hospitals are a global public health problem. Numerous individual- and population-level factors contribute to the emergence and spread of these pathogens. An individual-based model (IBM), formulated as a system of stochastically determined events, was developed to describe the complexities of the transmission dynamics of antibiotic-resistant bacteria. To simplify the interpretation and application of the model’s conclusions, a corresponding deterministic model was created, which describes the average behavior of the IBM over a large number of simulations. The integration of these two model systems provides a quantitative analysis of the emergence and spread of antibiotic-resistant bacteria, and demonstrates that early initiation of treatment and minimization of its duration mitigates antibiotic resistance epidemics in hospitals. |
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| responsibles | Perthame |
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