Spontaneous formation and evolution of autocatalyctic set within compartments

old_uid9123
titleSpontaneous formation and evolution of autocatalyctic set within compartments
start_date2010/10/06
schedule18h-19h30
onlineno
detailsPremiere double seance
summaryBiological evolution came to existence with the first living organism and we are still only guessing about the mechanisms of chemical evolution that could have operated before this time. The replication-first theory envisions polymer strands capable of template replication, meaning that the sequence of molecules on the parent strand is replicated (with mutation) to the child strand by a topographic mapping between the parent and child strand. Others point out the extreme improbability of the spontaneous emergence of such polymers and turn to investigate the appearance of catalytic reaction networks that could have been capable of producing complex organic molecules, and eventually, DNA and RNA strands. The GARD model was demonstrated by Vasas et al to lack evolvability. Are any other systems capable of undergoing natural selection prior to the origin of template replicators? We examine the ability of autocatalytic sets of linear polymers to form spontaneously and to sustain heredity when enclosed in compartments. Unlike GARD they are capable of sustaining multiple attractors that selection can act upon, and of evolving by co-optive evolution. The chemical network motifs responsible for heredity are examined.
responsiblesLegrand