Transcriptional coding of stem and progenitor cells diversity in the postnatal forebrain

old_uid11497
titleTranscriptional coding of stem and progenitor cells diversity in the postnatal forebrain
start_date2012/06/08
schedule11h30
onlineno
location_infosalle de conférence Magendie
detailsInvité par Muriel Koehl.
summaryThe subventricular zone (SVZ) of the lateral ventricle contains stem cells that continue producing neurons throughout adulthood. This regions is however heterogeneous with neural stem cells located in defined regions of the SVZ being biased to acquire specific fates. I’ll present our current work aiming at mapping and sampling this heterogeneity. I’ll then illustrate how analyzing the SVZ as a 3D structure allows the identification of generic or lineage specific-transcription factors involved in the control of forebrain neural stem cells behaviors in health and pathologies.
responsiblesDeris