Mechanisms underlying limb regeneration in an adult vertebrate

old_uid11765
titleMechanisms underlying limb regeneration in an adult vertebrate
start_date2012/10/26
schedule15h
onlineno
location_infoAmphithéâtre Maurice Halbwachs
detailsGrand séminaire du Cirb (sur proposition de S. Vriz)
summaryThe most extensive repertoire of regenerative ability in adult vertebrates is found in the urodele amphibians (salamanders), and includes the limbs. Limb regeneration depends on intriguing mechanisms that include reprogramming of differentiated cells, specification of structures on an adult scale, and dependence on regenerating nerve axons. This background information helps us to approach the difficult questions about regeneration as an evolutionary variable. Why does a salamander regenerate its limbs while other tetrapod vertebrates cannot?
responsiblesMaloumian