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Human induced pluripotent stem cells to model neurodegenerative disorders| old_uid | 11942 |
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| title | Human induced pluripotent stem cells to model neurodegenerative disorders |
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| start_date | 2012/12/13 |
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| schedule | 11h |
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| online | no |
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| location_info | RdC, salle 01-02 |
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| details | Organisé par l’Axe I - Maladies neurodégénératives |
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| summary | In my group we are specialized in the generation of human induced pluripotent stem cells (iPSc) and their directed differentiation
into neurons and motor neurons to model
neurodegenerative diseases. The first part of my talk will focus on the modeling
of a fatal lysosomal storage disease causing neurodegeneration in affected children, the Sanfilippo B syndrome.
In the second part of my talk I will describe more recent results we obtained with the iPSc technology to model
Amyotrophic Lateral Sclerosis (ALS) and in particular ALS2, a juvenile recessive motor neuron disease. |
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| responsibles | Miles |
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