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Strategies for cognitive translation from animals to humans: knock-outs, neurogenesis, neuropsychiatric and neurodegenerative disease| old_uid | 12053 |
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| title | Strategies for cognitive translation from animals to humans: knock-outs, neurogenesis, neuropsychiatric and neurodegenerative disease |
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| start_date | 2013/02/04 |
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| schedule | 16h |
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| online | no |
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| details | Host: Neil Burgess |
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| summary | The use of animal models is an indispensible tool for the study of normal cognition, and for understanding and discovering treatments for disorders of cognition. A major goal in the use of the animal models of cognition is translation, the ability successfully to transfer our behavioural results in animals to clinical studies in humans (and, indeed, back again). To achieve this aim, cognitive tests in animals should be as similar as possible to those used in humans. However, many of the currently most widely used animal behavioural tests are in fact very dissimilar to those used with human subjects. In my talk I will introduce the touchscreen approach to assessing cognition in animal models, which provides the ability to test rodents on tasks in many cases identical, in all important respects, to those we and others have used in humans. By taking such an approach we have a better chance than ever of achieving successful translation from mouse and rat to human in the study of normal cognition, and in discovering treatments for disorders of cognition. |
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| responsibles | Lawrence |
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