Physiology-Driven Models of Cortical Neurons & Networks: How Much Detail Do We Need?

old_uid12781
titlePhysiology-Driven Models of Cortical Neurons & Networks: How Much Detail Do We Need?
start_date2013/09/19
schedule12h
onlineno
detailsGNT Theoretical Neuroscience Seminar Series. This seminar has been organised by Flora Bouchacourt.
summaryPhysiological neurons and networks are highly complex in terms of their biophysical, biochemical, morphological and anatomical ingredients. How much of that detail do we have to include in a physiologically realistic model? I will first give some examples that seem to suggest that biophysical details really matter for dynamical phenomena at the network level, but will then review some evidence that, on the contrary, seems to imply that much of this detail can be safely neglected. It will furthermore be argued that 'physiologically highly realistic' does not at all imply 'as much biophysical detail as possible' (sometimes even to the contrary), and will introduce some of our 'highly-data-driven' predictive physiological modeling approaches.
responsiblesKoechlin