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Dissociable roles of dopamine and serotonin in learning and decision making| old_uid | 13998 |
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| title | Dissociable roles of dopamine and serotonin in learning and decision making |
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| start_date | 2014/05/19 |
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| schedule | 16h |
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| online | no |
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| details | Host: Jonathan Roiser |
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| summary | Serotonin and dopamine have been suggested to subserve motivationally opponent functions, but until recently this hypothesis had not been tested directly. I will present a study in which we investigated the dissociable roles of these neurotransmitters in a probabilistic reversal learning paradigm in nearly 700 individuals as a function of two polymorphisms in the genes encoding the serotonin and dopamine transporters. I will then zoom in on serotonin, whose role in motivation processing is much less well understood than for dopamine, and present two pharmacological studies in which we investigated the suggested role of serotonin at the interface of aversive processing and behavioural inhibition. |
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| responsibles | Lawrence |
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