Specification of synaptic connectivity by trans-synaptic interactions

old_uid14362
titleSpecification of synaptic connectivity by trans-synaptic interactions
start_date2017/09/22
schedule12h-13h
onlineno
detailsHosted by Bassem Hassan
summaryThe nervous system consists of billions of neurons that are precisely connected through synapses. Unraveling how neurons form appropriate synaptic connections during development is a key challenge in neuroscience and is essential to understand brain function and disease. Neural circuit formation critically relies on cell-cell recognition and communication mediated by cell-surface ligands and receptors. The complexity of the cell-surface interactions that pattern precise synaptic connectivity is only beginning to emerge. In this seminar, I will focus on synaptic adhesion molecules and discuss novel findings on the role of these proteins in organizing connectivity, structure and function of the synaptic network.
responsiblesOliviero