Spatial cells and spatial behaviour on the Honeycomb maze

old_uid15964
titleSpatial cells and spatial behaviour on the Honeycomb maze
start_date2018/06/18
schedule15h
onlineno
location_infosalle 2
detailsGrand Séminaire (sur proposition d'A. Berthoz & M. Zugaro)
summaryThe Hippocampal Formation contains different types of spatial cells (place, head- direction,boundary, and grid cells) which together make up a cognitive mapping system. The cognitive map enables an animal to locate itself and objects such as food and water in a familiar environment, and to navigate towards or away from particular locations, for example, those containing food or danger respectively. There are several behavioral testing platforms for assessing an animal’ s knowledge of spatial location and its performance on tests of spatial navigation. Foremost amongst the latter is the Morris Water Maze which, although extremely successful, has several drawbacks for the assessment of behavior and perhaps more importantly is not ideally suited for single unit recording. I will describe a new behavioral testing apparatus, the Honeycomb Maze, which overcomes many of these disadvantages. In addition to describing several spatial factors influencing successful performance on this maze, I will describe the performance of animals with hippocampal damage and discuss preliminary data on the use of the maze to study place and grid cell activity.
responsiblesMaloumian