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Lipid dysfunction in neurodegenerative disease| old_uid | 16257 |
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| title | Lipid dysfunction in neurodegenerative disease |
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| start_date | 2018/09/24 |
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| schedule | 11h-12h |
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| online | no |
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| summary | Hugo Bellen, DVM, PhD is an Investigator of the Howard Hughes Medical Institute and a Professor in the Departments of Molecular and Human Genetics and Neurosciences at Baylor College of Medicine in Houston, Texas. He leads the Model Organism Screening Center of the Undiagnosed Diseases Network for the NIH in the USA.
Dr. Bellen studies human disease genes and has utilized novel technologies developed in his laboratory to manipulate flies to validate dozens of novel genes in which variants cause neurological disease in humans. His talk will focus on two topics. 1) The role of elevated levels of reactive oxygene species in lipid droplet formation in a variety of neurological disorders, including the role of ApoE4 in Alzheimer disease; 2) The toxic role of ceramide elevation in Parkinsonism and Parkinson Disease. |
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| responsibles | Oliviero |
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