Generating CRISPR mouse models for neurodevelopmental disorders

old_uid16260
titleGenerating CRISPR mouse models for neurodevelopmental disorders
start_date2018/09/14
schedule12h-13h
onlineno
location_infosalle 01-02
summaryCRISPR genome editing technology enables targeted genetic modification of virtually any species with unprecedented efficiency. For biomedical research, CRISPR technology offers unparalleled opportunities to develop accurate and sophisticated cell and animal disease models using virtually any species or cell type. Prof Thomas was an early adopter of CRISPR gene editing and has generated over 60 mutant mouse lines using this technology. His presentation will describe his recent research on mouse models of genetic epilepsy and intellectual disability that reveal new insights into the pathological mechanism and developmental origin of these debilitating conditions.
responsiblesOliviero