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How neuronal representations of space promote effective appetitive behaviour in mice| old_uid | 17148 |
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| title | How neuronal representations of space promote effective appetitive behaviour in mice |
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| start_date | 2019/01/14 |
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| schedule | 11h |
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| online | no |
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| details | invited by M.Bocchio for the postdocs and students of Inmed |
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| summary | Retrieving and acting upon memories of food-predicting environments are fundamental processes for animal survival. In my talk, I will present our latest work showing in mice that the behavioral manifestation of spatial appetitive memory requires a direct neural pathway from dorsal CA1 (dCA1) hippocampus to nucleus accumbens. This pathway engages dCA1 with a select population of accumbens parvalbumin-expressing fast-spiking interneurons, thereby sculpting the assembly activity of its postsynaptic medium-sized spiny neurons. An indirect pathway through dorsal subiculum is dispensable for appetitive memory, but contributes to spatial novelty detection. |
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| responsibles | Bernier |
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