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Moving toward a cellular-based understanding of theta generation in the hippocampus| old_uid | 17581 |
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| title | Moving toward a cellular-based understanding of theta generation in the hippocampus |
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| start_date | 2019/03/21 |
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| schedule | 14h |
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| online | no |
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| location_info | salle 235B |
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| summary | Oscillatory activities are a ubiquitous feature of brain recordings and
likely form part of the neural code. In particular, theta rhythms
(3-12Hz) in the hippocampus play fundamental roles in memory processing.
Can we understand how theta rhythms are generated from cellular
perspectives? It is challenging to address this question largely
because of the multi-scale nature of our brains. However, we need to
tackle this challenge as it is clear that cellular specifics can dictate
oscillatory network output and thus contribute to brain function and
neurological disease. In this talk I will describe our work that
focuses on intrinsic theta rhythms in the hippocampus due to use of a
whole hippocampus preparation. This allows a tight linking between the
models and experiment that can include well-defined cellular
considerations and so help lead to explanations and understanding of
theta rhythm generation from cellular perspectives. |
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| responsibles | Kushnir |
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