Latest developments in Neurophysiology of States of Consciousness: From Mechanistic Principles to Novel Diagnostic and Therapeutic Tools, by Jacob SITT (INSERM)

old_uid17990
titleLatest developments in Neurophysiology of States of Consciousness: From Mechanistic Principles to Novel Diagnostic and Therapeutic Tools, by Jacob SITT (INSERM)
start_date2019/10/31
schedule14h
onlineno
summaryUncovering the neural mechanisms that allow conscious access to information is a major challenge of neuroscience. An incomplete list of still openquestions include, What are the necessary brain computational properties to permit access to a stream of conscious contents? What is the relationship between conscious perception, self-awareness, and multisensory processing of bodily signals? How these processes change when the brain transitions to an ‘unconscious’ state (like sleep, anesthesia or pathological conditions)? Can we externally trigger state-of-consciousness (SOC) transitions using stimulation? In this presentation, I will present my work focus on these relevant scientific and clinical questions. I will present our latest developments including different pre-clinical and clinical experimental models (brain-injuries and/or anesthesia), neuroimaging methods (EEG, fMRI or brain/body interactions) and stimulation techniques (tES, auditory/somatosensory/visual stimulation). Overall I will try to demonstrate that the integration of multimodal neural information provides critical information to characterize the state-of-consciousness in physiological and pathological conditions and might help to predict novel optimal therapeutic strategies.
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