Theory of Orientation Selectivity in Mouse Primary Visual Cortex

old_uid18601
titleTheory of Orientation Selectivity in Mouse Primary Visual Cortex
start_date2020/12/14
schedule11h
onlineno
detailsDue to the current lockdown, you can participate to this seminar by streaming on ZOOM. https://incc-paris.fr/events/seminar-by-david-hanzel/
summaryThe connectivity principles underlying the emergence of orientation selectivity in the primary visual cortex (V1) of mammals lacking an orientation map (such as rodents and lagomorphs) are poorly understood. We present a computational model in which random connectivity gives rise to orientation selectivity that matches experimental observations. The model predicts that mouse V1 neurons should exhibit intricate receptive fields in the two-dimensional frequency domain, causing a shift in orientation preferences with spatial frequency. We find evidence for these features in mouse V1 using calcium imaging and intracellular whole-cell recordings.
responsiblesAgulhon