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Comparing brains across individuals and species via cortical folding patterns| old_uid | 18967 |
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| title | Comparing brains across individuals and species via cortical folding patterns |
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| start_date | 2021/04/22 |
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| schedule | 12h-17h |
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| online | no |
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| summary | A prominent feature of the human cerebral cortex is the presence of folds, or sulci. Even though cortical sulci look very different from one person to another, sulcal organisation is not at all random: it follows a topography that is highly conserved across human and nonhuman primates. Robust sulci-function relationships have mostly been demonstrated in the primary sulci (e.g. the central sulcus where the motor cortex is found), as these sulci tend to be more stable across individuals in terms of their shape, and relative positions on the cortex. In contrast, sulci-function links in secondary and tertiary sulci have been harder to study due to large inter-individual variabilities.
With the advent of modern neuroimaging methods and an accumulation of MRI brain scans, it is now possible to characterize the spatial, geometric, and topological variations of cortical sulci across many individuals and species, and to study their links to brain function. This promising line of work has revealed novel relationships between sulci and functional brain areas at the individual level beyond primary sulci, that are generalised across primates. Such powerful sulci-function links provide an important means of bridging brains across individuals and species for comparisons. |
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| responsibles | Bureau |
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