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Integrative modeling of Paramecium, a “swimming neuron”| old_uid | 19887 |
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| title | Integrative modeling of Paramecium, a “swimming neuron” |
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| start_date | 2022/02/01 |
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| schedule | 14h30-16h30 UTC+1 |
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| online | no |
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| details | Inscription au lien https://participations.ehess.fr/ |
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| summary | Paramecium is a unicellular organism that swims in fresh water using cilia. When it is stimulated (mechanically, chemically, optically, thermally, etc), it often swims backward then turns and swims forward again: this is called the avoiding reaction. This reaction is triggered by a calcium-based action potential. For this reason, it enjoyed a period of glory in the 1970s as a model organism for neuroscience. We have developed an integrative model that links electrophysiology and behavior, quantitatively constrained by experimental data. This model is a dynamical system coupled to the environment, which allows revisiting various neuroscientific themes (perception, adaptation, learning) in the context of an autonomous system, rather than within the stimulus-response paradigm. |
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| responsibles | Sarti, Petitot, Nadal |
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