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Insights from human-specific genes on the molecular mechanisms of synaptic development| title | Insights from human-specific genes on the molecular mechanisms of synaptic development |
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| start_date | 2024/11/29 |
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| schedule | 11h |
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| online | no |
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| location_info | salle de conférence Albe-Fessard |
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| summary | Synaptic connections assemble neurons into circuits and endow our brains with the capacity to sense, act, feel, think, interact and remember. In my talk, I will describe efforts in my lab towards understanding the cellular and molecular mechanisms of synaptic development in cortical circuits and their specific regulations in humans. I will illustrate how human-specific genes and molecular pathways linked to human evolution regulate the timing of synaptic maturation and cortical connectivity through intrinsic and activity-dependent mechanisms. I will discuss how these regulations support the emergence of characteristic features of the human brain and their link with neurodevelopmental disorders. |
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| responsibles | Perignon |
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Workflow history| from state (1) | to state | comment | date |
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| submitted | published | | 2024/11/18 15:19 UTC |
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