The timescale dynamics of epilepsies: from seconds to decades

titleThe timescale dynamics of epilepsies: from seconds to decades
start_date2025/01/13
schedule11h
onlineno
location_infosalle de conférence
summaryContinuous long-term recordings (months to years) in patients with epilepsy show that seizures are regulated in a circadian manner. Besides, these recordings allowed to prove the presence of a much slower rhythm (days to weeks) of seizures. They strongly suggest the existence of specific molecular processes that influence the time of occurrence of seizures. Both circadian and multidien rhythms are biological phenomena, common to many animals species and plants. I will show that cortical structures undergo dynamic reconfiguration of their molecular architecture in a daily manner in health and disease. Accounting for daily and multidien molecular rhythms is essential to our understanding of brain function and dysfunction.
responsiblesBurban