The semantic memory system as a conduit for flexible thinking – what have we learned from semantic dementia?

titleThe semantic memory system as a conduit for flexible thinking – what have we learned from semantic dementia?
start_date2025/04/14
schedule15h30
onlineno
location_infosalle comodate, B33 & online
summarySemantic dementia (SD) is a rare neurodegenerative disorder characterised by the progressive degeneration of the conceptual knowledge base. This syndrome has provided compelling insights into the neurocognitive architecture of semantic memory, highlighting its varied interactions with so-called episodic memory processes. It is now abundantly clear that semantic knowledge makes a fundamental contribution to autobiographical recollection and provides the essential scaffold for constructing novel future events. In this talk, I will present an overview of our work to date revealing how the progressive deterioration of semantic memory disrupts the capacity for autobiographical retrieval from the past, the ability to envisage the future, and expressions of creative cognition. Notably, these impairments seem intimately related to the emergence of repetitive and ritualistic behaviours in SD suggesting that semantic memory loss may drive an inflexible and rigid style of interacting with the world. As such, I hope to highlight the dynamic ways in which episodic and semantic representations interact in the service of complex feats of cognition, as well as to consider what it might be like to lose these uniquely human functions.
responsiblesGrégoire