Engineering Multiscale Imaging Technologies to Characterize Disease States: From Organs to Individual Cells

titleEngineering Multiscale Imaging Technologies to Characterize Disease States: From Organs to Individual Cells
start_date2022/11/14
schedule11h
onlineno
location_infolieu précisé ultérieurement
summaryThe ability to image at depth in biological tissue is critically important to diagnose and characterize disease states. Current approaches for biological imaging often leverage the use of confocal or 2–photon systems to accomplish high resolution imaging at increased depth. These tools are often used in combination with contrast agents including nanoparticles, organic dyes, and genetic reporters. Despite recent advancements, however, current optical techniques remain restricted to an imaging depth of ~1mm due to the scattering of light in tissues. To circumvent limitations in depth, the Smith lab integrates waveguides into clinical and research tools to provide new methods of cellular subtyping and tissue imaging capabilities. This talk will highlight a series of optical and photoacoustic imaging tools that have been developed in Dr. Smith’s lab to address the urgent need for non–invasive cancer detection and the characterization of neurological disorders, beyond current capabilities.
responsiblesPerrais, Thoumine