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Unraveling the effect of the locus coeruleus on brain states and dynamics with preclinical fMRI| title | Unraveling the effect of the locus coeruleus on brain states and dynamics with preclinical fMRI |
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| start_date | 2023/01/09 |
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| schedule | 11h |
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| online | yes |
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| visio | https://us02web.zoom.us/j/83888993899?pwd=ZFZ0STdQVmhESkI2bnVabWRWV0RpQT09 |
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| location_info | amphithéâtre & zoom |
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| details | invité par Davide Boido |
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| summary | The recent advancement of MRI-based tools for mapping brain function in rodents provides a great platform for discovering the determinants of functional (dys)connectivity, whether genetic mutations, environmental risk factors, or specific cellular and circuit dysfunctions. In my talk, I will describe our most recent contributions to the field, underlining the drawbacks of utilizing such a technique while also emphasizing the novel opportunities that this technology can provide.
I will also discuss how perturbational techniques can be used to dissect the fundamental aspects of fMRI coupling and reveal the causal contribution of neuromodulatory systems to brain network activity, with a particular emphasis on the locus coeruleus / noradrenergic system.
These examples highlight how rodent functional imaging has the potential to increase our understanding of the origins and drivers of human functional connectivity. |
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| responsibles | Blancho |
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Workflow history| from state (1) | to state | comment | date |
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| submitted | published | | 2023/01/05 12:54 UTC |
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