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Simple principles in complex development: two case studies| title | Simple principles in complex development: two case studies |
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| start_date | 2025/10/13 |
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| schedule | 11h |
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| online | no |
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| location_info | salle de conférence |
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| summary | Biological systems display strikingly complex and adaptive dynamics. Yet beneath this apparent complexity, «simple» rules and constraints may govern developmental trajectories. In this talk, I will present two case studies that address different aspects of maturation. First, I will discuss the maturation of brain wiring in the nematode Caenorhabditis elegans. I will introduce a parsimonious model of brain wiring development that statistically reproduces the experimental trajectory up to the adult connectome. Second, I will turn to the maturation of behaviour, focusing on the locomotor development of the miniature fish Danionella cerebrum. Here, we identify a transition from continuous to burst-and-coast swimming that is not driven by a preprogrammed neural switch, but instead emerges as an energy-saving strategy directly tied to the animal’s swimming strength. Together, these works show how key aspects of biological development can be traced back to simple underlying principles — highlighting the role of physics in uncovering them. |
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| responsibles | Burban |
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Workflow history| from state (1) | to state | comment | date |
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| submitted | published | | 2025/10/03 11:37 UTC |
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