Neuromodulation of brain states

titleNeuromodulation of brain states
start_date2025/11/26
schedule11h
onlineno
location_infoamphithéâtre Neurocampus Michel Jouvet, Bât. 462
summaryThe sequence of vigilance states is tightly regulated, and sleep continuity is likely an essential feature of its function. Recent discoveries on local discontinuities in vigilance states in rodents and humans raise new challenges to define sleep/wake stability. Here I will discuss new data from our laboratory demonstrating cortex-wide complex dynamics across sleep/wake cycles using genetically encoded voltage sensors. I will also describe a new neuronal circuit that predicts the onset and duration of REM sleep, raising new hypothesis about the nature of the REM homeostat. Finally, I will describe attempts to non-invasively modulate arousal circuits and optimize sleep quality.
responsiblesNC