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The control of sequence working memory in the macaque brain| title | The control of sequence working memory in the macaque brain |
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| start_date | 2023/03/13 |
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| schedule | 11h |
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| online | no |
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| location_info | amphithéâtre & zoom |
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| details | Invited by Stanislas Dehaene & Florent Meyniel |
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| summary | To memorize a sequence, one must serially bind each item to its order. In this process, how the brain flexibly controls a given input to its associated order in sequence working memory (SWM) remains unknown. Here, we investigated the neural representations of the SWM control process using high-throughput electrophysiological recordings to record thousands of neurons in the frontal cortex of macaque monkeys performing delayed sequence-sorting tasks. We found separate representations of sensory and SWM at the population level within the same frontal circuitry, reflecting the control process through their organized neural dynamics. Item at each rank was sequentially entered into a common entry subspace and, depending on the sorting algorithm, flexibly and timely controlled into their associated rank-selective SWM subspaces. Crucially, neural activities in these subspaces can faithfully predict monkeys’ behavior in single trials. Thus, well-orchestrated neural dynamics in the frontal cortex underlie the flexible control of SWM. |
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| responsibles | Blancho |
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Workflow history| from state (1) | to state | comment | date |
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| submitted | published | | 2023/03/09 10:30 UTC |
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