Characterizing Motivation in Depression

titleCharacterizing Motivation in Depression
start_date2026/02/02
schedule15h15
onlineno
location_infoRoom B10
summaryDysfunction in motivation represents an important transdiagnostic facet of psychiatric conditions, associated with dopamine network dysfunction in animal models. Motivated behaviors can be modulated by a range of extrinsic/environmental or intrinsic factors, which might differentially contribute to depression symptomology. However, the role of intrinsic versus extrinsic motivation in depression remains poorly understood. In a series of experiments, distinct processes underlying intrinsic/extrinsic motivation were parsed, and their neural correlates examined via high-field MRI, in individuals with and without depression. A motivation-based neurofeedback intervention was delivered via pre-registered RCT, and individuals were tracked in the real-world via smartphone app. Findings and future directions will be presented.
responsiblesAllen