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Neural mechanisms for memory and emotional processing during sleep| title | Neural mechanisms for memory and emotional processing during sleep |
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| start_date | 2022/10/17 |
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| schedule | 11h-12h |
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| online | no |
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| location_info | Conference room R229 |
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| summary | The hippocampus and the amygdala are two structures required for emotional memory. While the hippocampus encodes the contextual part of the memory, the amygdala processes its emotional valence. During Non-REM sleep, the hippocampus displays high frequency oscillations called “ripples”. Our early work shows that the suppression of ripples during sleep impairs performance on a spatial task, underlying their crucial role in memory consolidation. We more recently showed that the joint amygdala-hippocampus activity linked to aversive learning is reinstated during the following Non-REM sleep epochs, specifically during ripples. This mechanism potentially sustains the consolidation of aversive associative memories during Non REM sleep. On the other hand, REM sleep is associated with regular 8 Hz theta oscillations, and is believed to play a role in the regulation of emotional reactions and the consolidation of emotional memories (emotional processing). Unraveling the fine neuronal dynamics related to REM sleep, Non-REM sleep and the transitions between states in the hippocampus-amygdala network will further our understanding of the implication of these sleep stages and related brain patterns in emotional processing. |
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| responsibles | Agulhon |
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Workflow history| from state (1) | to state | comment | date |
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| submitted | published | | 2023/06/29 13:13 UTC |
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