Genetic architecture of the autonomic nervous system

titleGenetic architecture of the autonomic nervous system
start_date2023/11/03
schedule11h30-12h30
onlineno
location_infoConference room R229
summaryA general structure for the autonomic nervous system, divided into sympathetic and parasympathetic arms, was codified by John Newport Langley at the beginning of the XXth century. We propose a revision of this scheme based on neuron types. The “sacral parasympathetic” outflow is revealed to bear no resemblance to the cranial one, and to be instead a caudal elaboration of the thoraco-lumbar sympathetic system. The midbrain pathway to the eye, considered parasympathetic, is shown to belong in a class by itself. Thus the current parasympathetic division of the autonomic nervous system turns out to be a mosaic of largely unrelated cell types, in line with its multifarious physiological functions, poorly subsumed under the popular “rest and digest” motto.
responsiblesAgulhon